antimicrobial susceptibility of stenotrophomonas maltophilia clinical isolates from blood samples in iran

introduction: stenotrophomonas maltophilia is a nosocomial multi drug resistant opportunistic pathogen which causes infections in vulnerable patients with cancer, cystic fibrosis and indwelling catheters. methods: 45 clinical s. maltophilia isolates were collected from blood samples and identified by biochemical tests. susceptibility to different antibiotics including co-trimoxazole, levofloxacin, minocycline, ticarcillin/clavulanic acid, chloramphenicol and ceftazidime were determined by disk diffusion and e-test methods. results: all isolates were resistant to ceftazidime and susceptible to co-trimoxazole and  11.1% were resistant to ticarcillin/clavulanic acid. conclusion: ceftazidime as one of the extended spectrum β-lactams was the least effective antibiotic. ticarcillin/clavulanic acid is one of the choosen antibiotics for s. maltophilia infections treatment. here, we report tcarcillin/clavulanic acid resistance in s. maltophilia isolates for the first time in iran.